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Bremelanotide is a compound that is currently under investigation for its potential uses in managing reperfusion injury, female sexual dysfunction or hemorrhagic shock. The chemical may also see success in managing modulate inflammation or limiting the effects of ischemia.

Study – Potential Use Erectile Dysfunction

One study has explored the potential use of bremelanotide as a replacement for natural peptide melanocyte stimulating hormones for the sake of treating erectile dysfunction.

• The goal of this study was to determine if the effects of bremelanotide stimulating sexual desire that was shown in male rats could be replicated in the brains of female rats. To do this, hormone primed female rats in a control group and a test group that were treated with bremelanotide and known to have consummatory sexual disorders was introduced to a group of male rats and the reactions were measured.

• Heart racing, hops and darts, pacing and customary sexual behaviors were assessed while the brain was stimulated. The stimulation of specific molecular markers within the brain was examined to determine arousal in the female subjects.

• Results indicated that the females saw an increase in sexual behavior when bremelanotide was applied to the limbic and hypothalamic regions of their brains. It is suggested that this was because the chemical that stimulated the mPOA terminals, leading to activated dopamine in the brain.

Additional study is necessary to determine the extent of the effects bremelanotide has on the brain and natural stimulating chemicals. Research companies buy bremelanodtide in our online store located right here at www.supplementsbuy.com

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What is PT-141(Bremelanotide) ?

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PT-141(Bremelanotide) is the first of a new class of drugs called melanocortin agonists being developed to treat sexual dysfunction. The mechanism of action of PT-141 (Bremelanotide) may offer significant safety and efficacy benefits over currently available products because it acts on the pathway that controls sexual function without acting directly on the vascular system. Clinical data indicates that PT-141 (Bremelanotide) may be effective in treating a broad range of patients suffering from ED. The nasal formulation of PT-141 (Bremelanotide) being developed is as convenient as oral treatments, is more patient-friendly than invasive treatments for ED, http://www.supplementsbuy.com such as injections and trans-urethral pellets, and appears to result in a rapid onset of action.
About Erectile Dysfunction (ED)
ED is defined as the consistent inability to attain and maintain an erection sufficient for sexual intercourse. The condition is correlated with increasing age, cardiovascular disease, hypertension, diabetes, hyperlipidemia and smoking. In addition, certain prescription drugs and psychogenic issues may contribute to ED. It is estimated that some degree of ED affects one half of all men over the age of 40 and that 150 million men worldwide suffer from erectile disfunction  

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PT-141, or bremelanotide, belongs to the new class of synthetic proteins that work as melanocortin agonists. It is a peptidic compound under new drug development process known as palatin technology. Its molecular formula is C50H68N14O10; its molecular weight/mass is 1025.2.

This new representative of peptides was synthesized just recently from melanotan-ppeptide, and till now is being participating in few clinical trials with animal models in different countries. To date, the biggest randomized controlled and double-blind clinical studies were done in 2004 and 2007 with looking at safety evaluation, pharmacokinetic features and its pharmacodynamics for males and females respectively. In the end of 2012 the second phase of clinical trial was finished and its results will be published soon.
PT-141’s primary feature is to have positive influence to sexual systemic dysfunction. Unlike other compounds and hormones bremelanotide doesn't affect the vascular system; instead this research compound works by stimulating melanocortin receptors, and that in turn leads to sexual stimulation and to modulation of inflammation.
This peptide is experimental and released for clinical and research use only.

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PT-141 Bremelanotide, is a synthetic peptide developed by Palatin Technologies to counter hemorrhagic shock and reperfusion injury. A peptide of the tanning agent Melanotan II, PT-141 also functions as a sex enhancement drug, and treats erectile dysfunction among male users. Erectile dysfunction (ED) is the inability of a male subject to maintain an erection sufficient for preformance. The condition is common among older men, and those who experience cardiovascular disease, hypertension and diabetes. PT-141 has also proven effective in improving the vigor or potency of men and women. Initial studies conducted by Palatin Technologies have shown that PT-141 stimulates the parts of the nervous system responsible for eliciting desire, and thereby increases the libidos of researchers. In contrast, PDE5s induce sexual desire via the vascular system, by increasing blood flow through the body. These kinds of pills have been proven to raise the instances of hypertension, and other cardiovascular diseases among users.
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Bremelanotide PT 141 is a research peptide developed by United States. PT-141 functions by activating the melanocortin 1 receptor and MC4R namely. Bremelanotide originally was tested for nasal spray delivery but was discontinued after concerns about side effects. Bremelanotide PT141, as Melanotan II, may cause spontaneous arousal enhancing effect. Unlike other supplements, pt 141 results do not act on the vascular body, but directly increases desires through the nervous system.

Bremelanotide PT-141 Protein Synthesis Information

Our PT141 delivers 99% purity ratings, HPLC quality tested PT-141 10MG. PT141 USA Company ensures good experience offering 2 day average guarantee order process times. Bremelanotide vials deliver on label claims and remains preserved when reconstituted with bac water for injection. Furthermore, bremelanotide triggers the melanocortin system to cascade variably to melanocortin receptors, more than PDE5 meds. Small-structure biologic melanocortin peptides molecule remains potent during shipping as well as in storage. Melanotan 2 and PT141 melanocortins do not require cold shipping to remain effective. Products stay potent and should not expire until years later when stored properly in the fridge or freezer.
PT-141 is a synthetic amino acid protein discovered during clinical trials using the Melanotan 2 for sunless tanning, photo-protection results from melanotans. Participants were documented as having experienced aphrodisiac reactions, leading to the further development of Bremelanotide PT-141. The melanocortin system targets receptors associated with desire through the melanocyte-stimulating hormone paths that cross the blood-brain-barrier. Potentially the powerful sex-drug results feeling an aphrodisiac experience amplifying arousal pt141 reviews have shown the ability to increase libido effects of both men and women.
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